Fonte: Clinical Neuropharmacology. 2017 May/Jun;40(3):113-119
Autori: Maschio M1, Dinapoli L, Zarabla A, Maialetti A, Giannarelli D, Fabi A, Vidiri A, Cantelmi T.
Epilepsy heavily affects the quality of life (QoL) of patients with brain tumor because in addition to taking treatments for the oncological illness, patients are required to live with the long-term taking of antiepileptic drugs (AEDs). The AEDs' adverse effects are common in these patients and can negatively influence their perceptions of their QoL.We conducted an observational pilot study in patients with brain tumor-related epilepsy to verify efficacy, tolerability, and impact on QoL and global neurocognitive performances of zonisamide (ZNS) in add-on.